Our results showed that the expression of the TNF-α in Group HF (172.48 ± 12.49 pg/ml), ADR (250.19 ± 9.63 pg/ml) and ADR + HF (339.19 ± 16.06 pg/ml) was higher than that in Group N (ADR + HF > ADR > HF ≫ N) (99.68 ± 9.58 pg/ml) both in serum (Figure 3(A)), and the same results were obtained in the renal tissue by the immunohistochemistry technique (Figure 3(B,C)). Here, TNF is linked to hydrops fetalis.