MAPT and frontotemporal dementia: For example, FTD patients with parkinsonism linked to chromosome 17 (FTDP‐17) show severe atrophy in the frontotemporal lobe, varying degrees of neurodegeneration in subcortical nuclei, and tau‐positive pretangles, neurofibrillary tangles, and glial fibrillary tangles (Foster et al., 1997).