XIST and hepatocellular carcinoma: One study reported that XIST was down-regulated in hepatocellular carcinoma tissues, and patients with lower XIST expression showed shorter OS rates than those with higher XIST expression [20]; the other study reported that XIST was down-regulated in cervical squamous cell carcinoma tissues, and higher XIST expression showed good prognosis than lower XIST expression [14], therefore, the data from these 2 studies could not be pooled.