Notably, conditioned medium from two different lung-derived fibroblast lines with XRCC1 KD, significantly stimulated the growth of non-small cell lung carcinoma-derived H1299 cells (Figure 4B and Supplementary Figure 4A) and lung carcinoma-derived A549 (Supplementary Figure 4B) cell lines. This evidence concerns the gene XRCC1 and non-small cell lung carcinoma.