TRIM52 and glioblastoma: TRIM52 knockdown significantly reduced the cell numbers of U87MG and A172 glioblastoma cell lines, but not the other two glioblastoma lines tested (Figure 1B), even though TRIM52 protein expression was equally reduced in all four glioblastoma cell lines (Figure 1A), and efficient knockdown was maintained throughout all days of the experiment (Supplementary Figure 1D).