Given that VCaP cells show the highest expression of CDK19 among a large number of cell lines (approximately 1000 cell lines) in the Cancer Cell Line Encyclopedia (CCLE) database (https://portals.broadinstitute.org/ccle/home), it is plausible that overexpression of CDK19 plays a predominant role in prostate cancer cell proliferation. The gene discussed is CDK19; the disease is cancer.