GSK3B and colorectal carcinoma: Consistent with our previous studies [12–15], GSK3β-specific small-molecule inhibitors AR-A014418 [46] and SB-216763 [47] reduced the proliferation of CRC cells (HCT116, SW480, LoVo, and HT-29) compared with the same cells treated with dimethyl sulfoxide (DMSO, diluent for inhibitors) (Supplementary Figure 2A).