Our results demonstrated that EIF3C slightly increased expression of divergent exosome biomarkers in vesicles of HCC cells (Figure 2F), increased RNA concentration ratios in exosomes (Supplementary Figure 2E), enhanced tubes formation of HUVEC cells (Figure 2G) and promoted the formation of new blood vessels in the transplanted matrix gel plugs in nude mice (Figure 2H and 2I). Here, EIF3C is linked to hepatocellular carcinoma.