An A to G single-nucleotide polymorphism (SNP) in MCP-1 enhancer region (rs1024611, originally designated as –2518 G or –2578 G) was found to be responsible for higher levels of MCP-1 production by monocytes upon inflammatory noxa [14], and has been associated to several chronic inflammatory conditions such as autoimmune disorders, atherosclerosis and chronic infectious diseases [15]. Here, CCL2 is linked to atherosclerosis.