To further identify the effect of BPIFB1 on the radioresponse of NPC cells, CNE2 and HONE1 cells were transfected with empty or BPIFB1 overexpression vectors, and then treated in a single session with doses of 0, 2, 4, 6, and 8 Gy. The gene discussed is BPIFB1; the disease is nasopharyngeal carcinoma.