SLC1A5, GLS, PYCR1 and PIK3CA were significantly expressed in breast tumours with high expression of SLC7A5 (p < 0.001), while the low expression of SLC7A5 was associated with high levels of p-mTORC1 (p < 0.001) (Table 6). The gene discussed is PIK3CA; the disease is breast neoplasm.