We also validated WNT3 for severe COPD (P = 4.27 × 10− 6) and DCBLD1 for %LAA-950 (P = 1.41 × 10− 4) for genes identified from GTEx-Lung using a lung transcriptome database from Lung-eQTL Consortium (Table 3). Here, WNT3 is linked to chronic obstructive pulmonary disease.