TREM2 and infection: These include genes that are involved in triggering receptors expressed on myeloid cells (TREM), TREM1 and TREM2 in the present study, which interact with microbial products that activate innate immunity responses of organisms [38]; and the SLC11A1 gene (solute carrier family 11 member 1), which encodes an iron transporter and also plays a key role in innate immunity against infection by intracellular pathogens [39].