IL7 and Hepatic fibrosis: In hosts infected with S. japonicum or mansoni, parasite eggs are trapped in hosts’ liver and induce severe liver granulomatous responses, which subsequently lead to liver fibrosis, circulatory impairment or even death.2, 3 Macrophage is one of the critical participants in development of the liver immunopathology initiated by parasite eggs in host liver.2, 8 In this study, we showed for the first time that IL‐7 induced in S. japonicum infection suppressed AMPK‐dependent macrophage autophagy and enhanced liver immunopathology.