PRF1 and neoplasm: However, the mechanisms of action behind this phenomenon are currently still unclear.5, 6, 7, 8, 9, 11 It has been confirmed that the anti‐tumour functions of DC‐CIK cells include the following points: (1) CIK cells can recognise tumour cells through different mechanisms and release toxic granules such as granzyme/perforin to cause tumour cell lysis, thus achieving the direct tumour cell killing function.