For example, C-X-C motif chemokine 12 (CXCL12) can promote chemotaxis but not chemokinesis in human blood cord stem cells.[36] Insulin-like growth factor (IGF) I and II can promote chemotaxis and chemokinesis of malignant mesothelioma cells.[37] Platelet derived growth factor is a known chemotactic growth factor for cells of mesenchymal origin.[33] Growth factor interactions can also alter the response of a cell. The gene discussed is CXCL12; the disease is malignant mesothelioma.