PLCB4 (which encodes phospholipase-C β4) was shown to be a YAP1-target gene [71], as inducing PLCB4 knockdown attenuated the growth of YAP1-transduced immortalized mesothelial cells, and YAP1-active (but not YAP1-non-active) MM cells [71]. This evidence concerns the gene YAP1 and Miyoshi myopathy.