Immune checkpoint inhibitors including anti-CTLA4 (tremelimumab and ipilimumab), anti-PD1 antibodies (nivolumab and pembrolizumab), and anti-PD-L1 antibodies (avelumab and durvalumab) are currently undergoing intensive investigation in relevant MM clinical trials [21,22,23]. This evidence concerns the gene PDCD1 and Miyoshi myopathy.