FYN and schizophrenia: FYN codes for a tyrosine kinase which phosphorylates glutamate metabotropic receptors and ionotropic NMDA receptors, which modulates their trafficking, subcellular distribution and function (Mao and Wang 2016a) In the most recent GWAS of schizophrenia FYN was identified as a “prioritized candidate gene” and an intronic marker, rs7757969, was significant at p = 4.8 × 10−8 (Li et al. 2017).