The affected CDSs, including genes involved in nucleotide synthesis (mutM and mutY), DNA repair or DNA/RNA folding, and recombination functions (recB, recC, recD, recF, recG, recJ, recN, recO, rdgC, rarA, recX, recR, uvrA, uvrB, uvrC, and uvrD), were detected in our CF P. aeruginosa isolates and in CF P. aeruginosa isolates *356 and *381 (Table S3). The gene discussed is RARA; the disease is cystic fibrosis.