In order to analyze cellular stability of YY1 mRNA and protein, two B-NHL cell lines representing different subtypes, namely BL cell line RAMOS and DLBCL cell line U2932-R2, were selected and maintained in presence of the transcriptional inhibitor actinomycin-D (ACT-D) for 30 min up to 48 h. Here, YY1 is linked to Burkitt lymphoma.