We next incubated ADPKD tissue sections with fluorescein-conjugated Lotus tetragonolobulus (LTL) or Dolichos biflorus agglutinin (DBA) lectins or with antibody against Tamm-Horsfall Protein (THP) to examine the tubular origin of GLI1 + cells. This evidence concerns the gene GLI1 and autosomal dominant polycystic kidney disease.