Western blot analyses demonstrated a mild increase (~3 fold) in RCMTs, including NSUN1, NSUN3, DNMT2 and hnRNPK, in the 5-AZA-resistant erythroid and monocytic leukaemia cell lines, M2AR and SCAR, as compared to the corresponding, originally 5-AZA-sensitive OCI-M2 and SC leukaemia cell lines, respectively (Fig. 1a). This evidence concerns the gene NSUN3 and leukemia.