Using a panel of EBNA3KO viruses in BL31 BL-derived cells, EBNA3A and EBNA3C were found to cooperatively repress the tumour suppressor and pro-apoptotic BCL-2-family member BIM (Bcl-2-interacting mediator of cell death) encoded by BCL2L11 [9]. Here, BCL2 is linked to neoplasm.