EGR1 and infection: Different viruses, such as the KSHV (Kaposi’s sarcoma-associated herpesvirus), HSV-1 (herpes simplex virus type-1), JCV (human polyomavirus JC virus), HIV (human immunodeficiency virus) and EBV (Epstein-Barr virus) are also capable of modulating the egr-1 gene function during infection [25,26,27,28,29].