Previous studies using CSPG4-specific mAbs have shown that CSPG4 is expressed on nearly 73% of primary TNBC patient specimens, malignant cells in pleural effusions from patients with TNBC, human TNBC cells and CICs cultured in vitro, and TNBC xenograft tumors grown in immunodeficient mice [5,28,30]. This evidence concerns the gene CSPG4 and Pleural effusion.