Figure 7 panel C shows the analysis of TTF1 transcript level in five thyroid cancer cell lines treated for 48 h with 10 nM panobinostat, 10 μM SAHA, and 1 μM Trichostatin A. The level of TTF1 was significantly down regulated in FTC133, BCPAP, and 8505C cells treated with 10 nM panobinostat; whereas, in TPC1 and C643 cells, an up-regulation of TTF1 transcript was observed. Here, TTF1 is linked to thyroid gland carcinoma.