These data, including the treatment with nanomolar concentration of panobinostat, confirmed the previous study of Furuya and colleagues showing the re-expression of SLC5A5 (NIS), TPO (thyroperoxidase), and Tg (Thyroglobulin) mRNA after treatment with HDACi depsipeptide and Trichostatin A in poorly differentiated and anaplastic thyroid cancer in vitro and in vivo [37]. The gene discussed is TPO; the disease is thyroid gland undifferentiated (anaplastic) carcinoma.