Recently, TLR4 was reported to be highly expressed in cancers, including colon cancer [20, 26], pancreatic ductal adenocarcinoma [18], oral squamous cell carcinoma [31], ovarian epithelial cancer [28], non-small lung cancer [33] and hepatocyte carcinoma [27]. This evidence concerns the gene TLR4 and pancreatic ductal adenocarcinoma.