BSG and breast carcinoma: Previous findings from functional experiments have shown that CD147 is an indicator of tumor prognosis [6] and it can promote cancer cell migration, invasion and metastasis by enhancing the activity of matrix metalloproteinases by digesting the components of the extracellular matrix in breast cancer, lymphoma, oral squamous cell carcinoma, glioma, melanoma, lung cancer, bladder and kidney carcinomas and ovarian cancer [7–13].