Above the basis of Ang-2 promoting lung cancer A549 cell migration and metastasis, the alterations of the EMT-related epithelial indicator (E-cadherin), mesenchymal marker (Vimentin, VIM), and transcriptional factors (Snail and Twist) expression that involved in lung cancer development were analyzed in Figure 4F and 4G. The gene discussed is SNAI1; the disease is lung cancer.