TP53 and neoplasm: Each plasma sample was independently analyzed through Delly to identify translocations detectible without correlated tumor DNA: patient E's somatic TP53 intron 1 translocation was confidently detected, and a new translocation was discovered in patient H, which also involved the intron 1 of TP53 at chromosome 17 position 7588196 with chromosome 22 position 43579550 (Figure 2D).