Besides these signaling pathways, we found an enrichment in pathways involved in tumor development including: inflammation mediated by chemokine and cytokine, cell cycle, Ras (57), oxidative stress response (58), p53 (59), ubiquitin proteasome (60), JAK/STAT (61), p38 MAPK (62), angiogenesis, and EGF receptor signaling pathway (Table 5). The gene discussed is TP53; the disease is neoplasm.