MAPT and Pick disease: In a recent autopsy study of 21 individuals with Pick's disease (PiD), tau lesions (FTDL-tau) were detected in some of the same regions as the pTDP-43 pathology in pTDP-43 bvFTD cases but not always at the same phases, e.g., orbital gyri, superior and middle temporal gyri (PiD phase 1, one case), middle frontal and anterior cingulate gyri, striatum, primary somatosensory neocortex (PiD phase 2, three cases), agranular motor neocortex, precerebellar nuclei of the brainstem (PiD phase 3), primary visual neocortex (PiD phase 4) (Irwin et al., 2016).