Being the first report on these mutations in conjunctival melanoma, this finding is reminiscent of cutaneous melanoma, in which KRAS mutations are rare but occur in a mutually exclusive fashion with NRAS mutations.11 In the proposed TCGA (The Cancer Genome Atlas) genomic classification of cutaneous melanoma, mutations in all three RAS genes are grouped together as RAS-mutated melanomas. The gene discussed is NRAS; the disease is malignant conjunctival melanoma.