In agreement with the studies showing impaired glucose homeostasis, our own data in adeno-Cre-treated p53-floxed mice showed fasting hypoglycemia and a concomitant accumulation of gluconeogenic amino acids under starvation, altogether suggesting an impairment of glucose homeostasis in absence of hepatic p53 under starvation [38]. This evidence concerns the gene TP53 and Hypoglycemia.