Abnormalities in the production and the circulating levels throughout specific periods of gestation and in the relative variations of the several glycoforms of hCG have been associated with a large array of pregnancy complications, such as miscarriages [2], fetal chromosomal anomalies [3], preeclampsia [4,5], disturbances in fetal growth and development [6], gestational trophoblast diseases [7], etc. The gene discussed is CGB5; the disease is preeclampsia.