Consistent with the effects of PPARβ/δ in adipose tissue, it has been reported that overweight patients with mixed dyslipidaemia who were administered the PPARβ/δ agonist MBX-8025 for 8 weeks presented favourable trends in their body fat percentage, lean body mass and waist circumference, although the differences did not reach statistical significance [30]. The gene discussed is PPARD; the disease is inherited lipid metabolism disorder.