Currently available U.S. Food and Drug Administration (FDA) approved assays for BC diagnosis include the ImmunoCyt test (Scimedx Corp), the nuclear matrix protein 22 (NMP22) immunoassay test (Matritech), and multitarget FISH (UroVysion) (Fradet and Lockhard, 1997; Kawauchi et al., 2009; Krüger et al., 2003; Moonen et al., 2007; Sarosdy et al., 2006; Skacel et al., 2003; Yafi et al., 2015). The gene discussed is NUMA1; the disease is breast cancer.