Furthermore, depending on the cancer type for which [111In]SB3 + PA will be used for tumor detection pre- and intra-operatively, the application should be compared to that using other radiotracers under investigation or applied for similar purposes, e.g., lymphoscintigraphy for sentinel lymph node biopsy in breast cancer patients and PSMA radio-guided surgery in prostate cancer patients [21, 46]. This evidence concerns the gene FOLH1 and breast cancer.