CD274 and non-small cell lung carcinoma: One phase II trial currently ongoing at MD Anderson Cancer Center (NCT02525757) that considers the timing of immunotherapy is evaluating the safety and efficacy of atezolizumab, a monoclonal antibody targeting PDL1, in combination with standard chemoradiation (carboplatin and paclitaxel plus conventional 2-Gy fractionated radiation) for unresectable locally advanced NSCLC.