GLO1 and Seizure: Moreover, recombinant inbred strains of C57BL/6J and DBA/2J mice (BXD) that inherited a genomic duplication of GLO1 showed an approximately twofold increase in GLO1 expression and an association with increased susceptibility to epileptic seizures at high atmospheric pressure (McCall and Frierson, 1981; Plomin et al., 1991; Distler et al., 2013).