Further, NMZL displayed enrichment of mutations in the epigenetic modifiers KMT2D, CREBBP, EZH2, and TET2, which clearly separated NMZL from other SBCL entities, especially from SMZL and EMZL (p ≤ 0.05, Fisher’s exact test). Here, TET2 is linked to nodal marginal zone B-cell lymphoma.