BCL6 and nodal marginal zone B-cell lymphoma: In this study we aimed to comprehensively characterize the genetic background of NMZL using WES, targeted HTS, and aCGH, with a special emphasis on sharpening the diagnostic borders between NMZL and other closely related SBCL entities such as EMZL, SMZL, LPL, and BCL, U. Importantly, to rule out FL (mimicking NMZL), only cases proven to be t(14;18)-negative and BCL2-positive, and, in case of weak BCL6-positivity, without BCL6 rearrangement, were included in the NMZL cohort.