RPGR and retinal disorder: Two additional patients in our cohort were found to have either an in-frame deletion (c.2203_2226del) or duplication (c.2919_2939dup) in ORF15 of RPGR, which were not interpreted as disease-causing due to the relatively frequent occurrence of such variants in the normal population, although the patient with the duplication revealed a phenotype compatible with RPGR-related retinopathy.