In the Cox model, 4 independent predictors of tumor recurrence were identified: alcoholism (HR: 1.443; 95% CI: 1.062–1.960, p = 0.019), high AFP level (HR: 1.499; 95% CI: 1.185–1.897, p = 0.001), tumor size > 3 cm (HR: 1.562, 95% CI: 1.219–2.001, p < 0.001) and King’s score grade 3 (HR: 1.770, 95% CI: 1.318–2.378, p < 0.001). This evidence concerns the gene AFP and alcohol drinking.