In addition, real-time quantitative PCR confirmed the expression alteration of these apoptosis-related genes in PBMCs between SLE-PH and SLE-PL (Fig. 8h), which is consistent with the gene expression profiles in Peli1-deficient B cells that stimulated by noncanonical NF-κB inducer. The gene discussed is PELI1; the disease is systemic lupus erythematosus.