CRH and Anxiety: Others have found that the C-terminal 38-41 amino acids of human teneurins have sequence identity (up to 12%) with certain corticotropin-releasing factor peptides (Lovejoy et al., 2009), and that peptides corresponding to the C-terminal 38-41 amino acids of teneurins can modulate anxiety-related behavior and dendritic spine density in the hippocampus of rats following introduction of the peptide into the right lateral ventricle (Tan et al., 2011).