IL7 and infection: Since in addition to tumour immune modulation there are many other factors that affect the level of immune responses—e.g., unrelated infections which lead to an active immune response and increased secretion of IL-7 (as in HIV infections [55] or A. benhamiae infections [56]), making accurate predictions regarding tumour detection times (based on both tumour and immune biomarkers) might depend significantly on the status of immune response in each patient.