Given that murine skin abscesses are replete with high NO· levels early on and transition to hypoxia at later time points (both limiting respiration)[7], it is not surprising that we found the F1F0 ATPase operon to be required for fitness at days 3 and 7 in our Tn-Seq experiment (S3 Table). The gene discussed is DNAH8; the disease is Cutaneous abscess.