This syndrome can be considered a mosaic RASopathy because it is caused by postzygotic pathogenic variants in HRAS (HRas Proto-Oncogene, GTPase), KRAS (KRAS Proto-Oncogene, GTPase), or the NRAS (NRas Proto-Oncogene, GTPase) genes (115, 116). Here, KRAS is linked to RASopathy.