In addition to NF1, atypical manifestations, such as familial spinal neurofibromatosis, multiple spinal ganglioneuromas, optic gliomas, or Lentigines, Electrocardiographic abnormalities, Ocular hypertelorism, Pulmonary stenosis, Abnormalities of genitalia, Retardation of growth and Deafness (LEOPARD) syndrome, have been associated with NF1 mutations. Here, NF1 is linked to neurofibromatosis, familial spinal.