In addition, there is difference in ALDS2*2 carriers with certain disease in East Asia with respect to locality, for example, the number of Fanconi anemia patients with ALDH2*2 in Japan and Korea [112, 113] is far higher than in China or Taiwan, where the percentage of ALDH2*2 carriers is higher i.e., > 40% in Taiwan. The gene discussed is ALDH2; the disease is Fanconi anemia.