In stratified analyses of main malignant type, significant effect was observed between the high level of TRIM29 in digestive system cancer and poorer OS (random-effects model: pooled HR = 1.84; 95% CI: 1.24–2.72; P = 0.002) and no significant results were found in other types cancer (random-effects model: pooled HR = 1.03; 95% CI: 0.55–1.90; P = 0.000) (Figure 3A). The gene discussed is TRIM29; the disease is cancer.